Structure and Function of Proteins 2010: Exercises

Several subjects of the course are further treated in the following exercises, introducing basic computational tools used in analysis of structure and function of biological molecules.

1. Exercise 1:Introduction to DEEP-VIEW
2. Exercise 2: Secondary structure: alpha helices and beta sheets
3. Exercise 3: Structural conservation of proteins: The globin family as an example.
4. Exercise 4: Effect of mutations on structure and function of molecules. Examples: T4 lysozyme and Lambda-repressor
5. Exercise 5: Prediction of secondary structure. Does the local sequence determine secondary structure?
6. Exercise 6: Structure similarity without sequence similarity, fold recognition.
7. Exercise 7: Protein families
8. Exercise 8: Homology modeling.
9. Exercise 9: Protein adaptation to extreme environments
10. Exercise 10: Structure-function relationship in proteins
11. Exercise 11: DNA structure and Protein-DNA interaction: The Zinc Finger motif
12. Exercise 12: Protein-DNA interaction: The Helix-Turn-Helix and the Basic Leucine Zipper motif.

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